Drugs

Which of the following is the amount of 20% w/w benzocaine ointment required to be added to a suitable diluent ointment to prepare 5 kg of a 2.5% w/w benzocaine ointment?

Following drugs lower the interocular pressure
A. Pilocarpine
B. Latanoprost
C. Atropine
D. Tiotropium
Choose the correct answer from the options given below:

As per the Drugs and Cosmetics act and rules the good manufacturing practice is included under schedule

Which of the following combination shows antagonism?

Which of the following anti-depressant is a selective serotonin reuptake inhibitor (SSRIs)

Oral anti-diabetic metformin is a

Prazosin is used for treatment of

Select the incorrect statement regarding Tricyclic Antidepressants (TCAs)

All the following cardiovascular drugs are phosphodiesterase 3-inhibitors except.

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: The modified Noyes - Whitney equation states that larger the surface area of a drug, higher is the dissolution rate.
Reason R: the surface area increases with decreasing particle size.
In the light of the above statements, choose the most appropriate answer from the options given below

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Haloperidol is a preferred drug for acute schizophrenia and Huntington's disease.
Reason R: Parenteral administration by intramuscular route is possible in acute cases
In the light of the above statements, choose the most appropriate answer from the options given below:

Which of the following is a unique boron containing drug which acts as a proteasome inhibitor in anti cancer therapeutics.

Which of the following anti-malarial drug is contraindicated during pregnancy.

Which of the following is not used as tonicity contributor in sterile products?

Which of the following material is not used as enteric coating material for tablets?

Bancroft's rule is related to determination of

Avicel is a trade name of

Partition coefficient (log p) of various drugs can be determined using

Considering apothecary system 300 minims of the fluid is equal to

Propantheline has been found to reduce absorption rate of

Which of the following class of drugs is not OTC product?

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R):
Assertion (A): Cefuroxime axetil is an oral form of the first generation parenteral cephalosporin cefuroxime.
Reason (R) : The axetil form of the drug, an acetoxy ethyl ester of cefuroxime has increased lipid solubility, better absorption and oral bioavailability.
In the light of the above statements, choose the most appropriate answer from the options given below.

Which one of the following is the INCORRECT statement?

Glutathione (GSH) conjugation takes place by

Which one is the correct statement about drug metabolism?

Which one is the most stable conformation of acetylcholine?

Levorphanol (1) and dextrorphan (II) are stereoisomers of each other. Identify the true statement about I and II.

Atropine has served as a prototype molecule for which class of drugs?

What are the possible drug-receptor interactions?

Identify the true statement:
A. Phenylephrine has less a and ẞ activity than norepinephrine.
B. Metaproterenol is selective ẞ2-agonist.
C.Norepinephrine is immediate precursor of dopamine.
D. Dopamine has very good oral activity.
Choose the most appropriate answer from the options given below:

Given below are two statements :
Statement-I Cocaine and procaine are benzoic acid derivatives and both are known to cause allergic reactions.
Statement-II Structurally, cocaine contains tropine nucleus, whereas procaine doesn't
In the light of the above statements, choose the most appropriate answer from the options given below.

Match List I with List II

List I		List II
A	Six membered-oxygen containing compound	I	Pyran
B	Five-membered-nitrogen containing	II	Triazole
C	Six-membered-nitrogen containing	III	Pyrimidine
D	Xanthine nucleus	IV	Caffeine

Choose the correct answer from the options given below:

Following drug is used as inhalational anaesthetic

Which of the following benzodiazepines is a short acting sedative hypnotics?

In steroidal aglycone portion of cardiac glycosides

Match List I with List II :

List I		List II
A.	Passive Diffusion	I.	Partitioning and accumulation of the drug in the tissue.
B.	Perfusion Process	II.	Carrier mediate membrane transfer process with energy (ATP)
C.	Active Transport	III.	Blood flow is the rate limiting step in distribution of drag
D.	Drug Affinity	IV.	concentration without energy Molecules movement from high concertation to low (ATP).

Choose the correct answer from the options given below:

Which of the following is a incorrect statement

Tween 60 is chemically known as:

Elementary osmotic pump delivery systems are used for _____drugs

Glyceryl monostearate is used as

Which size of particles gives better bioavailability of digoxin

Which of the following anti-fungal drug is effective in treating kala-azar?

First-line antiretroviral regimens for adults is

Which of the following anti-cancer drugs is orally active triazine methylating agent and is also a drug of choice for glioma and other brain tumors?

Which of the following drugs is NOT a first line anti-tubercular drug?

Which of the following is a safer drug to be prescribed in diabetes during pregnancy?

Which of the following CNS stimulant is an analeptic drug?

All bacteriophage having nucleic acid core covered by a protein coat known as

Which of the following statements is NOT true about 'endotoxins'?

Artemisinin is an antimalarial drug and chemically it is

Cardenolides and bufadienolides are cardiac glycosides and chemically differ with respect to

Supercritical fluid chromatography utilises this supercritical fluid as a mobile phase

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R):
Assertion (A): Gold Beater's Test is performed for determining the presence of True tannins in a crude drug sample.
Reason (R) : Clove and Coffee contain pseudotannins.
In the light of the above statements, choose the most appropriate answer from the options given below.

Match List I with List II

List I		List II
A	Analeptic drug	I	Morphine
B	Central depressants of motor function	II	Picrotoxin
C	Analgesic drug	III	Tropane alkaloids
D	Hallucinogenic	IV	Cannabis

Choose the correct answer from the options given below:

Given below are two statements, one is labelled as Assertion (A) and the other is labelled as Reason (R):
Assertion (A): Liebermann Burchard Test is positive for Digitalis, Dioscorea and strophanthus.
Reason (R) : Digitalis, Dioscorea and strophanthus have sterol ring containing chemical constituents.
In the light of the above statements, choose the most appropriate answer from the options given below.

Give below are two statements:
Statement I: Aromatase Inhibitors include both steroidal and non steroidal compounds.
Statement II: Tamoxifen, Estrone. Testolactone and Nor-ethindrone are the examples of Aromatase Inhibitors
In the light of the above statements, choose the most appropriate answer from the options given below:

Lycopodium spore methods help to determine the _______of given drug samples.

Diazepam is first metabolized by _________?

What is the relation between dopamine, epinephrine and nor - epinephrine ?

Melphalan belongs to the following class of antineoplastic agents.

Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Dexamethasone is five fold active than Prednisolone for anti-inflammatory action.
Reason R: Dexamethasone is the florinated derivative of prednisolone.
In the light of the above statements, choose the most appropriate answer from the options given below:

The configuration at 1 and 2 is

How many chiral carbon atoms are there in the penicillin. molecule ?