Alcohol, Phenols And Ethers

When Acetophenone ethylene ketal reacts with dilute hydrochloric acid in water , it undergoes acid hydrolysis. The reaction breaks the ketal back into the original carbonyl compound acetophenone and ethylene glycol.

The phenoxide ion then undergoes methylation with methyl iodide (Mel) to form anisole (methoxybenzene, ) .Anisole undergoes Friedel-Crafts acylation with acetyl chloride in the presence of . The methoxy group ( ) is an ortho/para-directing group. However, the major product is usually the para product due to steric hindrance at the ortho position. undergoes the haloform reaction with NaOCl , where the methyl ketone group ( ) is converted to a carboxylic acid group ( COOH ) and the methyl group is cleaved off as chloroform ( ).