Molecular Biology Applied Genetics

If cystine is 20 percent guanine will also be 20 percent due to base pairing leaving 60 percent for adenine and thymine Since adenine pairs with thymine in equal amounts the adenine content will be 10 percent

Semiconservative replication of DNA was demonstrated by Meselson and Stahl Double helical structure of DNA was proposed by Watson Crick and Wilkins Adenosine Monophosphate synthesis was studied by H Khorana Synthesis of alanine tRNA was part of H Khoranas work

A transversion mutation occurs when a purine is substituted by a pyrimidine or a pyrimidine is substituted by a purine This contrasts with transition mutations where purines replace purines or pyrimidines replace pyrimidines

Sanger used dinitrofluorobenzene to study the structure of insulin by determining its amino acid sequence