Significance Of Mitosis

Cohesin is a protein complex that holds the two sister chromatids together after DNA replication, maintaining their cohesion until anaphase during cell division.
- Securin inhibits separase until anaphase.
- Separase cleaves cohesin to allow chromatid separation.
- APC (Anaphase Promoting Complex) regulates progression through mitosis.

Chromosomes are most condensed and aligned in the center of the cell during metaphase, making this the best stage to observe chromosome structure under a microscope.
- In prophase, chromosomes start condensing.
- In anaphase, chromosomes separate.
- In telophase, chromosomes de-condense.

Chromosomes are most condensed and aligned in the center of the cell during metaphase, making this the best stage to observe chromosome structure under a microscope.
- In prophase, chromosomes start condensing.
- In anaphase, chromosomes separate.
- In telophase, chromosomes de-condense.

Chromosomes are most condensed and aligned in the center of the cell during metaphase, making this the best stage to observe chromosome structure under a microscope.
- In prophase, chromosomes start condensing.
- In anaphase, chromosomes separate.
- In telophase, chromosomes de-condense.