Factors Affecting Enzyme Catalysis Reaction

Given below are two statements:

Statement I:	Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat.
Statement II:	When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor.

In the light of the above statements, choose the correct answer from the options given below:
1. Statement I is false but Statement II is true.
2. Both Statement I and Statement II are true.
3. Both Statement I and Statement II are false.
4. Statement I is true but Statement II is false.

Regarding catalytic cycle of an enzyme action, select the correct sequential steps:

A.	Substrate enzyme complex formation.
B.	Free enzyme ready to bind with another substrate.
C.	Release of products.
D.	Chemical bonds of the substrate broken.
E.	Substrate binding to active site.

Choose the correct answer from the options given below:
1. A, E, B, D, C
2. B, A, C, D, E
3. E, D, C, B, A
4. E, A, D, C, B