Disorders Of Muscular And Skeletal System

Low Ca²⁺ in the body fluid may be the cause of:

1. tetany

2. anaemia

3. angina pectoris

4. gout

Select the correct statement regarding the specific disorder of muscular or skeletal system.

1.	Muscular dystrophy - age-related shortening of muscles
2.	Osteoporosis- decrease in bone mass and higher chances of fractures with advancing age
3.	Myasthenia gravis- an autoimmune disorder which inhibits the sliding of myosin filaments
4.	Gout- inflammation of joints due to extra deposition of calcium

Select the correct statement with respect to locomotion in humans:

1.	Accumulation of uric crystals in joints causes inflammation
2.	The vertebral column has 10 thoracic vertebrae
3.	The joint between adjacent vertebrae is a fibrous joint
4.	The decreased level of progesterone causes osteoporosis in old people

Osteoporosis, an age-related disease of skeletal system, may occur due to:

1.	junction leading to fatigue
2.	high concentration of ca++ and Na+
3.	decreased level of oestrogen
4.	accumulation of uric acid leading to inflammation of joints

Which of the following muscular disorders is inherited?

1. Botulism

2. Tetany

3. Muscular dystrophy

4. Myasthenia gravis

Match the following columns and select the correct option:

	Column I		Column II
(a)	Gout	(i)	Decreased levels of estrogen
(b)	Osteoporosis	(ii)	Low Ca++ ions in the blood
(c)	Tetany	(iii)	Accumulation of uric acid crystals
(d)	Muscular dystrophy	(iv)	Autoimmune disorder
		(v)	Genetic disorder

Options:	(a)	(b)	(c)	(d)
1.	(ii)	(i)	(iii)	(iv)
2.	(iii)	(i)	(ii)	(v)
3.	(iv)	(v)	(i)	(ii)
4.	(i)	(ii)	(iii)	(iv)

Chronic auto immune disorder affecting neuro muscular junction leading to fatigue, weakening and paralysis of skeletal muscle is called as:

1.	Myasthenia gravis	2.	Gout
3.	Arthritis	4.	Muscular dystrophy

Given below are two statements:

Assertion (A):	Osteoporosis is characterised by decreased bone mass and increased chances of fractures.
Reason (R):	Common cause of osteoporosis is increased levels of estrogen.

In the light of the above statements, choose the most appropriate answer from the options given below:

1.	(A) is not correct but (R) is correct.
2.	Both (A) and (R) are correct and (R) is the correct explanation of (A).
3.	Both (A) and (R) are correct but (R) is not the correct explanation of (A).
4.	(A) is correct but (R) is not correct.

Which of the following is a correct match for disease and its symptoms?

1.	Muscular dystrophy	An auto immune disorder causing progressive degeneration of skeletal muscle
2.	Arthritis	Inflamed joints
3.	Tetany	high Ca2+ level causing rapid spasms.
4.	Myasthenia gravis	Genetic disorder resulting in weakening and paralysis of skeletal muscle