Antibiotics

To match the pairs, let’s understand the terms: - **Broad spectrum** antibiotics are effective against both Gram-positive and Gram-negative bacteria. → **Vancomycin** is a broad-spectrum antibiotic. Hence, A → II. - **Typhoid** is caused by *Salmonella typhi*, which is treated using **Chloramphenicol**, known for its effectiveness. → B → IV. - **Bactericidal** antibiotics kill bacteria directly. **Ofloxacin**, a fluoroquinolone, is a bactericidal agent. → C → V. - **Bacteriostatic** antibiotics inhibit bacterial growth. **Erythromycin**, a macrolide, is bacteriostatic. → D → III. So the correct matching is: A – II, B – IV, C – V, D – III

A. Broad Spectrum – Vancomycin (II): Vancomycin is known to be effective against a wide variety of bacteria, including both Gram-positive and Gram-negative types. B. Typhoid – Chloramphenicol (IV): This drug was historically the first antibiotic effective against typhoid fever, caused by *Salmonella typhi*. C. Bactericidal – Ofloxacin (V): Ofloxacin is a fluoroquinolone that kills bacteria by inhibiting DNA gyrase, making it bactericidal. D. Bacteriostatic – Erythromycin (III): Erythromycin is a macrolide that inhibits protein synthesis in bacteria, thus only stopping their growth (bacteriostatic).